Genes and mutations associated with addictions and substance dependence
If you tested your DNA with a personal genomics service like 23andMe, DeCODEme, FTDNA's Family Finder or another testing company, you can learn more about your risk factors for hundreds of diseases. Many of these SNP's are tested but not (yet) part of the report provided by personal genomics companies. This is free extra information.
We recommend that you install the SNPTips add-on for Mozilla Firefox to browse these pages. It allows you to upload your DNA results in the browser and show instantly which allele variant you have for each of the SNP listed below.
List of genetically determined addictions and substance dependence with their associated genes and SNP's
Alleles : This list comprises positive, neutral and negative traits
and conditions. Therefore we won't refer to risk factor like for diseases
here. Correlated alleles can be either strongly
associated (over 3x higher chances) or moderately
associated (up to 3x higher chances) with each condition/trait.
In some cases the allele can be negatively correlated
(lower chances). Depending on the testing company, sometimes A is reported
as T, and G is reported as C, or vice-versa.
Testing companies :
A = 23andMe (all versions) ; A2* = 23andMe (v2 only) ; A2 = 23andMe (v2 & v3) ; A3 = 23andMe (v3 only)
B = DeCODEme Bold letters indicate that the SNP is part of the official report, and is therefore likely to be more reliable. Only SNP's in the official report are listed for deCODEme.